Veregen: Adult Dosing

Dosage forms: 15% oint

genital/perianal warts, external

apply 0.5 cm per wart tid

Max: duration 16wk; Info: for immunocompetent pts

Veregen: Peds Dosing

This information is currently unavailable or not applicable for this drug.

Veregen: Contraindications/Cautions

• hypersens. to drug/class/compon.
• avoid sun/UV light exposure (genital/perianal area)
• avoid use on open wounds

Veregen: Drug Interactions

This information is currently unavailable or not applicable for this drug.

Veregen: Adverse Reactions

Serious Reactions

• local pain/inflammation
• phimosis
• superinfection
• desquamation
• application site rxn, severe
• erosion/ulceration
• hypersensitivity rxn
• lymphadenitis, regional

Common Reactions

• erythema
• pruritus
• burning
• pain/discomfort
• erosion/ulceration
• edema
• induration
• rash, vesicular
• desquamation
• lymphadenitis, regional
• discharge
• phimosis
• hypersensitivity rxn
• bleeding

Veregen: Safety Monitoring

Pregnancy: C

Lactation: Safety Unknown

Monitoring Parameters: no routine tests recommended

Veregen: Pharmacology

Metabolism: unknown; CYP450: unknown; Info: minimal systemic absorption

Excretion: unknown; Half-life: unknown

Class: Other Genitourinary, Other Dermatologics

Mechanism Of Action
exact mechanism of action unknown; may have anti-oxidative activity

Veregen: Manufacturer/Pricing

Manufacturer: PharmaDerm DEA/FDA: Rx

Veregen: Patient Education

• Generic Name: kunecatechins (topical)

• Pronounced: koo ne KAT e kins

• Brand Name: Veregen

What is the most important information I should know about kunecatechins?

Before using kunecatechins, tell your doctor if you have human papilloma virus (HPV), HIV or AIDS, or a weak immune system (from disease or medications such as steroids, chemotherapy, or radiation treatments).

Kunecatechins will not cure genital or anal warts, and will not keep you from spreading the warts to other people through sexual intercourse or skin-to-skin contact. Kunecatechins will not treat genital warts that are caused by the human papilloma virus (HPV).

Keep using kunecatechins until your warts have completely cleared. Do not use this medication for longer than 16 weeks without your doctor's advice.

Call your doctor if your warts do not clear up, or if they go away and then come back after treatment.

Talk with your doctor about safe methods of preventing transmission of genital warts during sex.

What is kunecatechins?

Kunecatechins is an herbal product made from green tea leaves.

Kunecatechins is used to treat external (on the outside of the body) genital and anal warts in adult patients.

Kunecatechins will not cure genital or anal warts, and will not keep you from spreading the warts to other people through sexual intercourse or skin-to-skin contact. Kunecatechins will not treat genital warts that are caused by the human papilloma virus (HPV).

Kunecatechins may also be used for purposes other than those listed in this medication guide.

What should I discuss with my health care provider before taking kunecatechins?

Using this medication will not prevent you from passing genital warts to another person during skin-to-skin contact or sexual intercourse. Talk with your doctor about safe methods of preventing transmission of genital warts during sex.

Do not use this medication if you are allergic to green tea.

Before using kunecatechins, tell your doctor if you are allergic to any drugs, or if you have:

• human papilloma virus (HPV);
• HIV or AIDS; or
• a weak immune system (from disease or medications such as steroids, chemotherapy, or radiation treatments).

If you have any of these conditions, you may not be able to use kunecatechins, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether kunecatechins passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take kunecatechins?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Wash your hands before and after applying this medicine.

Kunecatechins is usually applied 3 times daily. Apply enough ointment to cover each wart, leaving a thin layer of ointment on the skin surface.

Do not wash the treated skin area just after applying this medication. Reapply the ointment after you swim, bathe, or shower.

Women using this medication should wash the ointment off before inserting a tampon into the vagina. You may accidentally get some of the medicine into your vagina if you insert a tampon while the ointment is on the outside of your vagina.

Men using this medication on an uncircumcised penis should wash underneath the foreskin each day.

Keep using kunecatechins until your warts have completely cleared. Do not use this medication for longer than 16 weeks without your doctor's advice.

Call your doctor if your warts do not clear up, or if they go away and then come back after treatment.

Kunecatechins ointment can stain clothing or bed sheets. Avoid getting the medicine on these surfaces. You may want to wear dark-colored clothing to prevent unwanted staining. Do not use a sanitary napkin or other protective barrier without your doctor's advice.

Store this medication in the refrigerator and do not allow it to freeze.

What happens if I miss a dose?

Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of applied kunecatechins applied to the skin is not expected to produce life-threatening symptoms.

What should I avoid while taking kunecatechins?

Avoid sexual intercourse while you have this medication on your skin. Wash the ointment off before having intercourse, even if you are using a condom. Kunecatechins can weaken the latex in a rubber condom, and an unintended pregnancy could occur.

Avoid touching the treated skin areas, or allowing another person to touch your treated skin after you have applied the ointment.

Kunecatechins is for use only on the outside of the body. Avoid getting this medication in your eyes, nose, or mouth or into your rectum, vagina, or the opening to your bladder.

Do not apply this medication to an open wound or broken skin.

Avoid exposing treated skin to sunlight or artificial UV rays (sunlamps or tanning beds).

What are the possible side effects of kunecatechins?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Wash off the ointment with mild soap and water and call your doctor at once if you have any of these serious side effects:

• severe redness, burning, or itching of treated skin;
• swelling, blisters, sores, or skin changes where the medicine was applied;
• hardening of the treated skin areas; or
• bleeding of treated skin.

Keep using the medication and talk with your doctor if you have only mild stinging, itching, or irritation.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect kunecatechins?

Before using kunecatechins, tell your doctor about all other genital wart treatments you have used or are still using.

There may be other drugs that can affect kunecatechins. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about kunecatechins written for health professionals that you may read.

What does my medication look like?

Kunecatechins is available with a prescription under the brand name Veregen Ointm. Other brand or generic forms may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Veregen: Pill Pictures

This information is currently unavailable or not applicable for this drug.